Your safety is our first priority. Learn more about key medication details, side effects, and other important information about your treatment.

Important Safety Information

DHEA (Dehydroepiandrosterone) and Pregnenolone are hormones naturally produced by the adrenal glands and serve as precursors to other hormones such as estrogen, testosterone, and progesterone. Supplementation may be prescribed off-label to support hormone balance, improve mood, cognition, libido, or manage symptoms related to aging or adrenal fatigue.

DHEA/Pregnenolone should only be used under the supervision of a licensed healthcare provider.

Do not take DHEA/Pregnenolone if you:

• Are pregnant, planning to become pregnant, or breastfeeding
• Have hormone-sensitive conditions such as breast, uterine, or prostate cancer
• Have severe liver, kidney, or heart disease
• Have a history of blood clots, stroke, or hormone-related conditions
• Are allergic to any ingredients in the compounded formula

Warnings and Precautions:

• May affect hormone levels—regular blood work is recommended to monitor testosterone, estrogen, and other hormone levels during treatment.
• Should be used with caution in individuals with mood disorders, PCOS, or a history of hormone-related health issues.
• Long-term or high-dose use may increase the risk of acne, hair loss, oily skin, facial hair growth (in women), or other androgenic effects.
• May interfere with certain lab tests—inform your provider about use before any medical testing.

Possible Side Effects

Contact your healthcare provider if you experience any of the following:

• Persistent or severe acne or hair growth
• Changes in mood, such as anxiety, irritability, or aggression
• Changes in menstrual cycle or libido
• Breast tenderness or enlargement
• Swelling, weight gain, or shortness of breath

Common Side Effects May Include:

• Headache
• Insomnia or restlessness
• Fatigue
• Oily skin or mild acne
• Mood swings
• Changes in appetite

Before Taking DHEA/Pregnenolone, Tell Your Healthcare Provider If You:

• Are taking other hormone therapies or supplements
• Have a history of hormone-sensitive cancers or conditions
• Have cardiovascular, liver, kidney, or thyroid issues
• Are under the age of 18 (not recommended for children or adolescents)

Drug Interactions

Tell your healthcare provider about all medications and supplements you take. DHEA and Pregnenolone may interact with:

• Hormone replacement therapies (e.g., estrogen, testosterone)
• Thyroid medications
• Blood thinners
• Anti-seizure medications
• Antidepressants or mood stabilizers

Administration & Storage:

• Take exactly as prescribed, usually in the morning to avoid insomnia.
• Do not exceed recommended dosage.
• Store at room temperature in a dry place, out of direct sunlight. Keep out of reach of children.

If you have questions or experience any side effects while taking DHEA/Pregnenolone, consult your healthcare provider for further guidance.